Prolotherapy

Prolotherapy uses a dextrose solution to treat selected painful joints, tendons and ligament attachments. The aim is to support a local repair response and improve comfort with movement.

Purpose and potential benefits

What prolotherapy is

Prolotherapy uses injections of hypertonic dextrose, a sugar solution more concentrated than body fluids, at selected joints or tendon and ligament attachments.

Potential benefits and limitations

Ligament laxity, or looseness, can allow excess joint movement. When this contributes to pain or a sense of giving way, prolotherapy may be considered with the goal of improving joint support and stability.

Potential benefits include less pain and more comfortable walking, lifting or exercise. Treatment may not help.

Planning and procedure

About the solution

Preparation and treatment sites

Before treatment, Dr. Coon will explain the solution and any numbing medicine it contains.

Dextrose is approved for intravenous use. Prolotherapy is an off-label use, meaning the FDA has not approved dextrose for this purpose.

How prolotherapy is thought to work

How prolotherapy is thought to work

Prolotherapy is intended to stimulate a local repair response at selected tendon or ligament attachments or within a joint. Dextrose may also influence pain signalling. How these processes contribute to outcomes in patients is still being studied.

Target selection and guidance

The diagnosis guides where the solution is placed. A plan may involve a joint, a tendon or ligament attachment, or several related sites.

Dr. Coon uses examination and relevant imaging to select the target. When ultrasound is used during treatment, it provides a view of the needle and nearby structures.

What a treatment visit may involve

A prolotherapy procedure generally includes:

  • Review of the treatment plan and consent
  • Positioning and preparation of the area
  • Placement of the solution at the agreed sites, with ultrasound when appropriate
  • Instructions for activity, comfort measures and follow-up

Dr. Coon will explain the proposed number of procedures and visit length beforehand. Your response guides decisions about further treatment.

Risks and other options

When another option fits better

Therapeutic options may include rehabilitation, activity changes, medication, further testing or watchful waiting with reassessment. A surgical opinion may be appropriate when the diagnosis calls for it.

Corticosteroid can provide temporary symptom relief in selected situations. Its risks depend on the tissue and frequency of use, including potential effects on tendons or cartilage. Dr. Coon is cautious about recommending corticosteroid or surgery before weighing other appropriate options. He will explain when either may serve your goals so you can make an informed decision.

An unclear treatment target, a concern outside the practice’s scope or a health factor that makes a procedure unsafe may call for a different plan. Dr. Coon will explain the next step.

Risks and health considerations

Temporary pain, stiffness or bruising can follow prolotherapy. Other possible risks include bleeding, infection, allergic reaction and injury to a nearby nerve or blood vessel.

Dr. Coon reviews medications, allergies, infection risk, bleeding concerns and other health factors before recommending treatment. Diabetes and medicines that affect bleeding or inflammation may require additional planning. Do not change medicines on your own.

Recovery and next steps

Recovery and aftercare

Soreness can affect more than one site when several tendon or ligament attachments are treated. Dr. Coon will explain how to manage soreness and adjust exercise and the demands placed on the treated tissues.

Your aftercare instructions will include when to contact the clinic and a plan to reassess your progress.

Cost and payment options

Your evaluation lasts an hour and costs $400. Dr. Coon explains the separate procedure fee and any included follow-up before scheduling. Payment is due before or at the time of your visit or procedure. NOVA Regen is a self-pay practice and does not bill insurance.

See fees, insurance and payment options.

If there is little or no improvement

Dr. Coon will help you define goals you can assess, such as walking, gripping or exercising with less pain, and set a time to review your response.

If those goals are not being met, he will review the diagnosis, treatment target and other therapeutic options with you before recommending another procedure.

Questions people ask

How many procedures would I need?

Dr. Coon will explain the proposed number and spacing before scheduling. Your response and reassessment guide decisions about further treatment.

Will it be uncomfortable?

The procedure can sting, and soreness may increase temporarily afterward. Dr. Coon will discuss comfort measures and activity guidance for the treated area.

Can I take anti-inflammatory medicines?

Dr. Coon will review your medicines and give instructions for the procedure. Do not stop or change medicines on your own. Changes to prescribed treatment should be coordinated with your prescribing clinician.

Is prolotherapy for teenagers?

NOVA’s standard service is for adults 18 and older. Athletes aged 16 to 17 with a focused sports injury may be considered case by case with a parent or legal guardian.

How treatment is scheduled

An evaluation helps you understand whether this treatment has a useful role in your care.

Plan your visit

Questions about fit? Request a 10-minute fit call.